Combining Botox with Other Anti-Aging Treatments: What You Need to Know

by: Linda Robison / Facial Fitness Specialist @ ABZ

A smiling woman sitting in dermatologist’s office after Botox and anti-aging treatment combination.

Wondering if it ok to combine Botox with other anti-aging treatments? The short answer: Yes!

Combining Botox with other procedures can be a great way to enhance your results—like peanut butter and jelly for your face, but with a little more planning.

Whether it’s fillers, peels, or other skin treatments, they can definitely complement Botox and give you that extra glow. That said, timing and the right combinations matter to get the best results.

In this ABZ guide we'll break it down into easy pieces so you can see how it all comes together!

Why combine treatments with Botox?

While Botox has many benefits, it basically has one main function. It's specifically designed to relax the muscles that cause dynamic wrinkles, like frown lines and crow's feet.

However, it doesn’t address other aging concerns like volume loss, sagging or dull skin texture. That's where other treatments, like dermal fillers or skin resurfacing (exfoliation), come in.

When combined, Botox smooths out wrinkles while other treatments restore lost volume and enhance skin texture—together, they offer a complete solution for a youthful, refreshed look.

Popular Botox Pairings to Enhance Anti-Aging:

Combining treatments may save time in your anti-aging routine by addressing multiple concerns in fewer appointments, making it a more efficient and cohesive approach to skincare.

  1. Dermal Fillers:  This "liquid facelift" combination addresses both wrinkles and volume loss. The toxin injection relaxes muscles, while fillers restore lost volume for a balanced rejuvenation. These can be done at the same appointment for minimal downtime.
  2. Microneedling:  Microneedling stimulates collagen production to improve texture and reduce scars. When paired with Botox, it results in firmer, smoother skin. Just remember, the two should be done in a certain order for best results. Learn more about microneedling after Botox here.
  3. Facials or Glowtox: Involves the combined of a toxin injectable with other skin treatments like facials or hyaluronic acid to enhance the overall glow of the skin. This treatment cleans and hydrates the skin, improving texture and radiance. The combo of these treatments address both surface concerns and underlying muscle activity.  Wondering when is the best time to get a facial with Botox? Find out here.
  4. Face Exercises: Facial exercises can help tone and lift the skin by working out your facial muscles. But, if you jump into these exercises right after Botox, they could interfear with how well the toxins work. Botox relaxes the muscles, so exercising them too soon might not give you the best results. Want to know what’s better for you? Check out facial exercises vs Botox here.

Key Considerations When Combining Botox with Other Treatments

This page is just a guide, but remember, it’s always best to listen to your professional when combining Botox with other treatments.

There are a few key things to keep in mind to get the best results, like timing and how different treatments work together.

Timing Matters:

  • Botox and fillers: Can often be done together for minimal downtime.
  • Botox and facials: Wait at least 2 weeks to avoid interfering with the toxin's settling process.
  • Botox and microneedling: Timing varies based on your provider’s recommendations. However, microneedling can be done before injections. 

Synergy of Treatments: Combining treatments that address different aspects of aging can amplify their effects. For instance, Botox smooths dynamic wrinkles, while a chemical peel or microneedling targets skin tone and texture.

ABZ Tip: Always discuss the sequence and timing of treatments with your provider to avoid overlapping recovery periods and maximize results

Aftercare Essentials

  • Avoid vigorous exercise or massage for at least 24 hours after Botox.
  • Use gentle skincare products and avoid exfoliants if combining with microneedling or peels.
  • Keep skin protected with SPF, especially after resurfacing treatments.

Final Takeaway:

Combining Botox with other anti-aging treatments can provide a comprehensive approach to facial rejuvenation. By addressing multiple aspects of aging, you can achieve a more youthful and refreshed appearance.

Always consult with experienced professionals to create a treatment plan that's right for you.


Question: Will combining treatments increase the risk of side effects?

Answer: Combining treatments can increase the risk of side effects if not done the right way. Always communicate with your provider about what treatments you plan to have done. It's important to follow instructions and make sure treatments are done in the correct order to avoid complications. Taking these steps can help you get the best results while keeping risks low.

Question: How soon can I combine Botox with other treatments?

Answer: Combining Botox with other treatments depends on the specific procedures involved. If done in the wrong order, some treatments may not be as effective. For example, certain treatments like chemical peels or microneedling should be done after Botox to avoid interfering with the toxin's effects. It's important to follow the timing recommendations of your healthcare provider to ensure safety and get the best results.

Question: Are there any treatments that should not be combined with Botox injections?

Answer: While many treatments can be combined with Botox, it's essential to consult with a qualified healthcare provider to determine the best plan tailored to your needs. Some treatments may require spacing—like a two-week gap—to ensure optimal results and minimize risks.

Question: How can I prolong the results of Botox and other treatments?

Answer: To make Botox and other treatments last longer, you can use the right skincare products. Some serums and creams help your skin heal and boost collagen, which can keep the results looking great for longer. Want to know more about how to make Botox last? Check out my How to Make Botox Last Longer page for more tips!

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